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PAEDIATRIC REFERENCE RANGES
REFERENCE RANGES FOR NEONATES AND CHILDREN
The importance of establishing a Reference Range for a particular population of subjects cannot be denied.
The availability of blood specimens from 'healthy' children led to the decision to use this group of subjects to establish Reference Ranges for neonates and children.
The particular population of children chosen was admitted to the urological ward for assessment of abnormal renal anatomy. These
children were clinically well at the time of admission, had a normal urea and creatinine and a mid-stream specimen of urine devoid
of cells, casts and organisms. Venous blood specimens were obtained during anaesthesia so as to avoid the stress of venepuncture
affecting the blood count parameters.
Cord blood was also collected from 'post delivery' mothers. These mothers acted as potential cord blood donors for the Australian Cord Blood Bank.
A total of 927 subjects were used for this study. The Reference Ranges were calculated using the Percentile
from each respective age group.
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RED CELL REFERENCE RANGES
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| AGE |
Hb
(g/l) |
RCC
(x 1012/l) |
Hct
(l/l) |
MCV
(fl) |
MCH
(pg) |
MCHC
(g/l) |
RDW-SD
(fl) |
RDW-CV
(%) |
| Cord blood |
121 191 |
3.34 5.40 |
0.37 0.60 |
101 117 |
33.0 38.0 |
302 341 |
61.9 81.4 |
15.5 19.2 |
| 1-7 d |
125 195 |
3.90 5.60 |
0.38 0.60 |
97 107 |
32.0 34.8 |
328 325 |
55.0 81.4 |
14.0 19.2 |
| 1-2 w |
120 185 |
3.80 5.50 |
0.36 0.55 |
95 100 |
31.5 33.6 |
333 336 |
50.0 70.0 |
12.0 18.0 |
| 2w - 3m |
102 130 |
3.38 3.94 |
0.30 0.38 |
84 98 |
29.0 33.8 |
333 355 |
39.9 56.6 |
12.6 16.0 |
| 3-6 m |
100 122 |
3.39 4.86 |
0.28 0.36 |
68 85 |
22.6 29.7 |
331 351 |
34.0 42.4 |
12.0 14.8 |
| 6m – 2y |
104 132 |
3.88 5.13 |
0.30 0.38 |
70 83 |
23.1 29.4 |
323 354 |
34.8 44.6 |
12.3 17.0 |
| 2-4 y |
107 136 |
3.86 5.01 |
0.31 0.38 |
73 85 |
24.8 29.9 |
329 359 |
34.3 44.1 |
12.1 15.6 |
| 4-8 y |
110 139 |
3.96 4.92 |
0.32 0.39 |
74 86 |
25.5 30.6 |
332 360 |
34.6 42.7 |
11.9 14.9 |
| 8-12 y |
113 143 |
3.98 5.15 |
0.33 0.41 |
75 86 |
25.7 30.6 |
335 361 |
35.3 41.0 |
12.0 14.1 |
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WHITE CELL REFERENCE RANGES
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| AGE |
WCC (x109/l) |
N (%) |
L (%) |
M (%) |
E (%) |
B (%) |
| Cord blood |
9.6 30.4 |
39 73 |
13 47 |
4 15 |
0 7 |
0 2 |
| 1-7 d |
7.5 21.0 |
20 73 |
30 70 |
4 15 |
0 7 |
0 2 |
| 1-2 w |
6.8 20.0 |
15 60 |
35 75 |
4 15 |
0 7 |
0 2 |
| 2w - 3m |
6.4 12.1 |
11 44 |
40 80 |
4 12 |
1 7 |
0 2 |
| 3-6 m |
5.6 14.1 |
7 35 |
53 83 |
3 14 |
0 6 |
0 1 |
| 6m – 2y |
5.4 13.6 |
14 55 |
37 79 |
2 12 |
0 6 |
0 1 |
| 2-4 y |
4.9 12.8 |
24 67 |
28 64 |
2 11 |
0 7 |
0 1 |
| 4-8 y |
4.7 12.3 |
32 71 |
20 59 |
2 10 |
0 8 |
0 1 |
| 8-12 y |
4.7 12.2 |
37 70 |
22 55 |
2 10 |
1 8 |
0 1 |
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| AGE |
N(A) x109/l |
L(A) x109/l |
M(A) x109/l |
E(A) x109/l |
B(A) x109/l |
NRBC |
| Cord blood |
4.4 21.0 |
2.5 9.1 |
0.6 4.1 |
0.0 1.3 |
0.0 0.4 |
1 24 |
| 1-7 d |
1.5 15.3 |
2.3 14.7 |
0.3 1.5 |
0.1 1.3 |
0.0 0.4 |
| 1-2 w |
1.0 12.0 |
2.4 15.0 |
0.3 1.5 |
0.1 1.3 |
0.0 0.4 |
| 2w - 3m |
0.8 4.9 |
3.8 7.6 |
0.3 1.2 |
0.1 0.8 |
0.0 0.2 |
| 3-6 m |
0.5 4.4 |
3.4 9.8 |
0.2 1.1 |
0.0 0.7 |
0.0 0.1 |
| 6m – 2y |
1.1 6.0 |
2.7 8.9 |
0.2 1.1 |
0.0 0.6 |
0.0 0.1 |
| 2-4 y |
1.7 6.7 |
2.0 6.6 |
0.2 1.0 |
0.0 0.6 |
0.0 0.1 |
| 4-8 y |
1.8 7.7 |
1.6 5.1 |
0.1 1.0 |
0.0 0.6 |
0.0 0.1 |
| 8-12 y |
1.8 7.6 |
1.7 4.5 |
0.2 0.9 |
0.1 0.6 |
0.0 0.1 |
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PLATELET REFERENCE RANGES
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| AGE |
PLT (x 109/l) |
PDW (fl) |
MPV (fl) |
| Cord blood |
195 434 |
9.5 14.5 |
8.9 11.8 |
| 1-7 d |
200 500 |
9.4 14.5 |
8.7 11.8 |
| 1-2 w |
250 600 |
9.4 14.5 |
8.7 11.8 |
| 2w - 3m |
270 645 |
9.4 14.0 |
8.7 11.0 |
| 3-6 m |
296 686 |
8.5 12.3 |
8.1 10.5 |
| 6m – 2y |
205 553 |
8.4 13.1 |
7.9 10.8 |
| 2-4 y |
214 483 |
8.4 13.1 |
8.0 10.9 |
| 4-8 y |
205 457 |
9.0 14.2 |
8.4 11.5 |
| 8-12 y |
187 415 |
9.5 14.2 |
8.6 11.5 |
© Gillian Rozenberg (April 1999)
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